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Monday, January 18, 2010

SIRT1 - DNA Protection & Repair

From USNews:
...maintain their telomerase levels: switching from regular to nonfat dairy products, adding two or three servings of fruits and vegetables to their diet, or doing just a few minutes of daily meditation, for example. The same may be true for other longevity boosters such as calorie restriction, which is thought to extend life span by boosting SIRT1, a protein involved in protecting and repairing DNA (and thus protecting against potential killers like heart disease and cancer). Cutting calorie intake by a hunger-pang-producing one third might help people live about 20 percent longer, suggests David Sinclair, a professor of pathology at Harvard Medical School who conducted studies, similar to the monkey one, in mice. He says reducing calories by a smaller amount—say, 50 calories a day—could moderately boost SIRT1.
in reference to:
"maintain their telomerase levels: switching from regular to nonfat dairy products, adding two or three servings of fruits and vegetables to their diet, or doing just a few minutes of daily meditation, for example. The same may be true for other longevity boosters such as calorie restriction, which is thought to extend life span by boosting SIRT1, a protein involved in protecting and repairing DNA (and thus protecting against potential killers like heart disease and cancer). Cutting calorie intake by a hunger-pang-producing one third might help people live about 20 percent longer, suggests David Sinclair, a professor of pathology at Harvard Medical School who conducted studies, similar to the monkey one, in mice. He says reducing calories by a smaller amount—say, 50 calories a day—could moderately boost SIRT1."
- Calorie-Restricted Diets and Other Ways to Avoid Aging - US News and World Report (view on Google Sidewiki)

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